Measuring quality of life in children with obstructive sleep disorders

L M de Serres1, C Derkay, S Astley

  • 1Division of Pediatric Otolaryngology, Children's Hospital and Regional Medical Center, University of Washington, Seattle, USA. LMD54@columbia.edu

Insights

The OSD-6 instrument reliably measures health-related quality of life in children with obstructive sleep disorders (OSDs). This validated tool effectively detects changes after adenotonsillectomy, improving patient care.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Quality of Life Research

Background:

  • Obstructive sleep disorders (OSDs) significantly impact children's health-related quality of life (HRQOL).
  • Validated disease-specific instruments are crucial for assessing HRQOL in pediatric OSD patients.

Purpose of the Study:

  • To validate a disease-specific HRQOL instrument, the OSD-6, for children diagnosed with obstructive sleep disorders.
  • To assess the reliability, validity, and responsiveness of the OSD-6 in pediatric patients.

Main Methods:

  • A prospective cohort study involving 100 caregivers of children (ages 2-12) with OSDs secondary to adenotonsillar hypertrophy.
  • The 6-item Obstructive Sleep Disorder-6 (OSD-6) instrument was administered at baseline and post-adenotonsillectomy.
  • Test-retest reliability, internal consistency, construct validity, and responsiveness were evaluated.

Main Results:

  • The OSD-6 demonstrated good test-retest reliability (ICC = 0.74).
  • Construct validity was supported by correlations with global QOL measures (R = -0.62 to -0.63).
  • The instrument showed large responsiveness to clinical change post-surgery (standardized response = 2.3).

Conclusions:

  • The OSD-6 is a reliable, valid, and responsive instrument for assessing HRQOL in children with OSDs.
  • It is suitable for detecting clinical changes following adenotonsillectomy.
  • The OSD-6 is easily administered and valuable for clinical practice.
Abstract

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