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Screening Assay for Oxidative Stress in a Feline Astrocyte Cell Line, G355-5
Published on: July 13, 2011
Is there epidemiologic evidence that anti-oxidants protect against disorders in cognitive function?
1Epidemiology, Demography, Biometry Program, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Ave, 3C-309, Bethesda, MD 20892 USA. launerl@exmur.nia.nih.gov
Abstract:
Experimental studies have identified several pathways through which oxidative stress could adversely affect cognitive function and increase the risk for dementia. Anti-oxidant supplements have been proposed as interventions for secondary or primary prevention against dementia. The existing observational studies and randomized trials examining anti-oxidants and cognitive function outcomes are reviewed. A discussion is provided of methodologic limitations of existing studies and possible directions for future investigations.
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