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Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
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Structural evidence for the evolution of pyrogenic toxin superantigens

D T Mitchell1, D G Levitt, P M Schlievert

  • 1Department of Biochemistry, University of Minnesota Medical School, 6-155 Jackson Hall, 321 Church St. SE, Minneapolis, MN 55455, USA.

Journal of Molecular Evolution
|December 16, 2000
PubMed
Summary

Pathogenic bacteria like Staphylococcus aureus and Streptococcus pyogenes produce pyrogenic toxin superantigens (PTSAgs). These toxins share structural similarities, suggesting an evolution through recombination of smaller motifs.

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