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[Cowpox and catpox infection. 2 Clinical case reports].

B Feuerstein1, M Jürgens, E Schnetz

  • 1Dermatologische Universitätsklinik, Hartmannstrasse 14, 91052 Erlangen.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 16, 2000
PubMed
Summary

Cowpox/catpox infection, characterized by skin lesions, can occur after contact with cows or cats. Diagnosis involves clinical signs, electron microscopy, PCR, and serology for effective management.

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Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Dermatology

Background:

  • Cowpox and catpox are zoonotic viral diseases caused by orthopoxviruses.
  • These infections can present with painful, hemorrhagic vesicles and black crusts, particularly on the hands, fingers, face, or neck.
  • A history of contact with infected animals, such as cows or cats, is a key indicator.

Observation:

  • Two female patients developed typical skin lesions consistent with cowpox/catpox infection.
  • Both patients had a history of recent contact with cows or cats.
  • The clinical presentation included painful, possibly hemorrhagic vesicles or black crusts.

Findings:

  • Clinical diagnosis of cowpox/catpox infection is supported by characteristic skin lesions and patient history.

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  • Diagnostic confirmation can be achieved through electron microscopy (detecting cytoplasmic inclusions histologically), polymerase chain reaction (PCR) for virus identification, cell culture, and serological tests for virus-specific antibodies.
  • The study highlights the utility of these diagnostic tools in identifying the infection.

    • Implications:

    • Early and accurate diagnosis of cowpox/catpox is crucial for appropriate patient management and preventing potential spread.
    • Understanding the diagnostic approaches, including viral identification and serological testing, aids clinicians in confirming the infection.
    • The report emphasizes the importance of considering cowpox/catpox in differential diagnoses for patients presenting with specific skin lesions and relevant animal contact history.