Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progress in renal transplantation.

C G French1, P Belitsky, J G Lawen

  • 1Department of Urology, QEII Health Science Center, Dalhousie University, Halifax, Nova Scotia, Canada.

The Canadian Journal of Urology
|December 16, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A randomized double-blind placebo controlled trial of oral acyclovir in renal allograft recipients.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses·2012
Same author

MDR1 C3435T polymorphisms correlate with cyclosporine levels in de novo renal recipients.

Transplantation proceedings·2006
Same author

Caseating granulomas on the glans penis as a complication of bacille calmette-guérin intravesical therapy.

Reviews in urology·2006
Same author

Bladder perforation during laparoscopic donor nephrectomy.

The Canadian journal of urology·2005
Same author

Third dose of basiliximab in pediatric renal transplantation.

Transplantation proceedings·2004
Same author

Therapeutic monitoring of cyclosporine in kidney transplantation: the Halifax experience.

Transplantation proceedings·2004
Same journal

Smarter, Not More: The Rationale for Reducing Systematic Cores in the MRI-Targeted Biopsy Era.

The Canadian journal of urology·2026
Same journal

Ten Years of Progress in Advanced Prostate Cancer at the AUA.

The Canadian journal of urology·2026
Same journal

Electroacupuncture for sperm improvement in varicocele: a case report.

The Canadian journal of urology·2026
Same journal

Transperineal approach for penetrating injury of corpus spongiosum and bulbous urethra caused by vesicourethral foreign body: a case report.

The Canadian journal of urology·2026
Same journal

Penile fracture and concomitant severe urethral trauma-a case report and discussion of surgical approach.

The Canadian journal of urology·2026
Same journal

Management of retained bullet fragments from posterior urethra after gunshot wound: a case report.

The Canadian journal of urology·2026
See all related articles

Renal transplantation in Canada has seen successes, but challenges remain in managing older patients with complex conditions and preventing chronic rejection. Future efforts focus on personalized therapies, minimizing toxicity, and enhancing organ donation.

Area of Science:

  • Nephrology
  • Transplantation Medicine
  • Immunology

Background:

  • Renal transplantation has advanced significantly over the past decade.
  • Demographic shifts in donors and recipients in Canada are noted.
  • New immunosuppressive strategies aim to reduce toxicity.

Purpose of the Study:

  • To review successes in renal transplantation.
  • To analyze demographic changes in Canadian donors and recipients.
  • To explore advancements in immunosuppression and chronic rejection prevention.

Main Methods:

  • Literature review of current transplantation research.
  • Analysis of data from the Canadian Organ Replacement Register.
  • Examination of immunosuppressive regimens and toxicity profiles.

Related Experiment Videos

Main Results:

  • Transplant rates are stable, but the dialysis waitlist grows with older, sicker patients.
  • Standard triple therapy (calcineurin inhibitor, antimetabolite, corticosteroids) is common.
  • Newer monoclonal antibodies offer less toxicity for sensitized recipients.

Conclusions:

  • Future challenges include developing patient-specific therapies.
  • Minimizing immunosuppression toxicity is crucial.
  • Preventing chronic rejection and improving organ donation are key goals.