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Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
Published on: June 6, 2016
The spatial and temporal expression pattern of Nesp and its antisense Nespas, in mid-gestation mouse embryos
S T Ball1, C M Williamson, C Hayes
1Mammalian Genetics Unit, Medical Research Council, Harwell, Didcot, Oxfordshire, OX11 0RD, UK.
Mechanisms of Development
|December 19, 2000
Abstract:
We describe the spatiotemporal expression pattern of Nesp, and its antisense transcript, Nespas. We found non-complementary expression of these two oppositely imprinted transcripts during mouse embryogenesis, in a number of forming embryonic structures. Nesp expression was primarily seen in the somites and vasculature, whereas Nespas was mainly detected in the progress zone, mesenchyme and ectoderm of the limb, and the neural tube.

