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The intrinsic function of a motor system--from ion channels to networks and behavior
1Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden. sten.grillner@neuro.ki.se
Brain Research
|December 20, 2000
Abstract:
The forebrain, brainstem and spinal cord contribution to the control of locomotion is reviewed in this article. The lamprey is used as an experimental model since it allows a detailed cellular analysis of the neuronal network underlying locomotion. The focus is on cellular mechanisms that are important for the pattern generation, as well as different types of pre- and postsynaptic modulation. This experimental model is bridging the gap between the molecular and cellular level to the network and behavioral level.