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Darier's disease: a new paradigm for genetic studies in psychiatric disorders
Q Cordeiro1, D M Werebe, H Vallada
1Institute of Psychiatry, School of Medicine, Universidade de São Paulo, São Paulo, Brazil.
Sao Paulo Medical Journal = Revista Paulista De Medicina
|December 20, 2000
Abstract
Context:
One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes.
Case Report:
A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12.