Mania in neurologic disorders

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M F Mendez1

  • 1Neurobehavior Unit (116AF), Veterans Affairs Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA. MMendez@ucla.edu

Current Psychiatry Reports
|December 21, 2000
PubMed

Insights

Secondary mania can arise from neurologic disorders, distinct from primary manic-depressive illness (MDI). Prompt evaluation, including neuroimaging, is crucial for diagnosing and managing these cases.

Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Neurologic disorders can manifest as secondary mania, mimicking primary manic-depressive illness (MDI).
  • Distinguishing secondary mania is critical for appropriate patient management.
  • Neurologic causes are more common in older patients without a family history of MDI.

Purpose of the Study:

  • To highlight the importance of identifying neurologic causes of secondary mania.
  • To outline the diagnostic evaluation for patients presenting with new-onset mania.
  • To discuss management strategies for neurologic mania.

Main Methods:

  • Review of clinical presentations and diagnostic criteria for secondary mania.
  • Emphasis on thorough patient history and neurological examination.
  • Inclusion of neuroimaging and other selected tests for diagnosis.

Main Results:

  • Identified various neurologic conditions associated with secondary mania, including strokes, tumors, movement disorders, white matter diseases, trauma, infections, and dementia.
  • Stressed the need for a comprehensive evaluation to differentiate secondary from primary mania.
  • Highlighted the potential for treating the underlying neurologic disorder.

Conclusions:

  • New-onset mania necessitates a thorough evaluation to rule out underlying neurologic causes.
  • Early diagnosis and management of neurologic mania can improve patient outcomes.
  • Treatment involves addressing the primary neurologic condition and utilizing medications like anticonvulsants.

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