Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Glucocorticoid-induced osteoporosis.

P Boulos1, G Ioannidis, J D Adachi

  • 1St. Joseph's Hospital, McMaster University, 501 - 25 Charlton Avenue E, Hamilton, Ontario, L8N 1Y2, Canada.

Current Rheumatology Reports
|December 21, 2000
PubMed
Summary

Glucocorticoid-induced osteoporosis can be effectively treated and prevented. Bisphosphonates are the recommended therapy of choice for managing this condition, offering significant benefits.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterizing types and circumstances of fractures in the Canadian Multicentre Osteoporosis Study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2025
Same author

Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group.

Archives of osteoporosis·2022
Same author

Incremental costs of fragility fractures: a population-based matched -cohort study from Ontario, Canada.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
Same author

Fragility of results from randomized controlled trials supporting the guidelines for the treatment of osteoporosis: a retrospective analysis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2021
Same author

Exploring changes in bone mass in individuals with a chronic spinal cord injury.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020
Same author

A scorecard for osteoporosis in Canada and seven Canadian provinces.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020

Area of Science:

  • Endocrinology
  • Rheumatology
  • Pharmacology

Background:

  • Glucocorticoids are widely used medications with a known side effect of bone loss.
  • Glucocorticoid-induced osteoporosis (GIOP) poses a significant clinical challenge.
  • The precise biological mechanisms of GIOP are not fully understood.

Purpose of the Study:

  • To evaluate recent clinical trial data on therapies for GIOP.
  • To identify effective treatments for the prevention and management of GIOP.

Main Methods:

  • Systematic review of recently published clinical trials.
  • Analysis of drug efficacy in treating and preventing GIOP.

Main Results:

  • Bisphosphonates demonstrated significant benefits in clinical trials.
  • Effective therapies for GIOP have been developed despite limited mechanistic understanding.

Conclusions:

  • Bisphosphonates are the preferred therapeutic option for GIOP.
  • Treatment and prevention of GIOP are achievable with current pharmacological agents.

Related Experiment Videos