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Congenital leiomyomatous epulis: a case report with immunohistochemical study
Y Takeda1, M Satoh, S Nakamura
1Department of Oral Pathology, School of Dentistry, Iwate Medical University, Morioka, Japan. ytakeda@iwate-med.ac.jp
Pathology International
|December 21, 2000
Summary
A rare congenital soft tissue mass in infants, mimicking congenital epulis, was found to be composed of mature smooth muscle cells. This
Area of Science:
- Oral pathology
- Pediatric pathology
- Soft tissue tumors
Background:
- Congenital epulis is a rare benign tumor of the newborn gingiva.
- Accurate diagnosis is crucial for appropriate management.
- Differential diagnosis includes various congenital soft tissue lesions.
Observation:
- A rare congenital soft tissue mass on the alveolar ridge of an infant presented clinically as congenital epulis.
- Histologic examination revealed a conglomerate of spindle-shaped cells resembling smooth muscle.
- Immunohistochemistry showed positivity for smooth muscle markers (alpha-smooth muscle actin, HHF-35, desmin).
Findings:
- The lesion was histologically distinct from congenital granular cell epulis.
- The spindle cells were identified as mature smooth muscle cells.
- The nature of the lesion was proposed as hamartomatous or choristomatous.
Implications:
- The proposed term 'congenital leiomyomatous epulis' aids in precise classification.
- Understanding the smooth muscle origin is key for diagnosis and potential future research.
- This case expands the spectrum of rare congenital oral lesions in infants.
