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The conjunctivitis of solar (actinic) prurigo
M Magaña1, Y Mendez, A Rodriguez
1Department of Pediatric Dermatology, Hospital General de México, S. S./Universidad Nacional Autónoma de Mexico (UNAM), and Service of Ophthalmology, Hospital General de México, S.S., Mexico City, Mexico. dermatopatologia@hotmail.com
Pediatric Dermatology
|December 21, 2000
Summary
Solar (actinic) prurigo (SP) is a sunlight-induced reaction affecting children, particularly in the Americas. This study details conjunctival findings, aiding in better characterization of this condition.
Area of Science:
- Ophthalmology
- Dermatology
- Genetics
Background:
- Solar (actinic) prurigo (SP) is an abnormal reaction to sunlight.
- It predominantly affects Indian and mestizo populations in the Americas.
- SP commonly begins in childhood, with oral and ocular mucosa involvement in 30-50% of cases.
Purpose of the Study:
- To present the clinical and histopathologic conjunctival findings in children with SP.
- To identify key diagnostic criteria for SP based on conjunctival changes.
Main Methods:
- Clinical examination of conjunctival findings in 11 children with SP.
- Histopathologic analysis of conjunctival biopsies.
- Correlation of clinical and histopathologic features.
Main Results:
- Clinically significant findings included photophobia, pterygium, pinguecula, hyperemia, Trantas' dots, hyaline exudate, and follicles.
- Histopathologic analysis revealed epithelial changes (epidermoid metaplasia, absence of goblet cells) and stromal changes.
- Diagnostic stromal changes included lymphocytic infiltrates with eosinophils, melanosis, and solar elastosis.
Conclusions:
- The study identified a constellation of clinical and histopathologic criteria for SP.
- These criteria are valuable for improving the characterization and diagnosis of solar (actinic) prurigo in children.