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Meningiomas.

Chamberlain1

  • 1Department of Neurology, Southern California Kaiser Permanente, 1011 Baldwin Park Boulevard, Room 1912, Baldwin Park, CA 91706, USA. Marc.C.Ch am berlain@kp.org

Current Treatment Options in Neurology
|December 21, 2000
PubMed
Summary

Meningiomas, common brain tumors, are often benign and treated with surgery. For recurrent or aggressive cases, stereotactic radiotherapy and immunochemotherapy offer alternative or advanced treatment options.

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Area of Science:

  • Neurosurgery
  • Oncology
  • Radiation Oncology

Background:

  • Meningiomas are extra-axial brain tumors predominantly affecting middle-to-late adult women.
  • While 90% are benign, atypical (6%) and malignant (2%) forms exist.
  • Surgical resection is the primary curative treatment for most meningiomas.

Purpose of the Study:

  • To review treatment modalities for meningiomas.
  • To highlight the role of radiotherapy and immunochemotherapy in managing complex cases.

Main Methods:

  • Review of current therapeutic strategies for meningiomas.
  • Discussion of surgical resection, radiotherapy, and immunochemotherapy.

Main Results:

  • Complete surgical resection offers a curative outcome for most meningiomas.
  • Stereotactic radiotherapy (SRT) is an effective alternative for specific patient groups and tumor locations.
  • Immunochemotherapy shows modest success for recurrent or aggressive meningiomas.

Conclusions:

  • Meningioma management involves a spectrum of treatments tailored to tumor characteristics and patient factors.
  • SRT is increasingly used as an alternative to surgery in select cases.
  • Immunochemotherapy provides options when surgery and radiotherapy fail or are not feasible.

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