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The EMBL nucleotide sequence database.

G Stoesser1, W Baker, A van den Broek

  • 1EMBL Outstation-The European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. stoesser@ebi.ac.uk

Nucleic Acids Research
|January 11, 2000
PubMed
Summary
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The EMBL Nucleotide Sequence Database offers free access to updated genetic sequences through daily data exchange with international collaborators. It provides various network services and tools for sequence similarity searching, aiding molecular biology research.

Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database is a key resource for genetic information.
  • It operates in collaboration with international partners like the DNA Data Bank of Japan (DDBJ) and GenBank at the National Center for Biotechnology Information (NCBI).

Purpose of the Study:

  • To describe the maintenance, data submission, and access methods for the EMBL Nucleotide Sequence Database.
  • To highlight the database's role in facilitating molecular biology research through data sharing and analysis tools.

Main Methods:

  • Daily data exchange between collaborating databases (EMBL, DDBJ, GenBank).
  • Utilizing Webin for individual submissions and automated procedures for large-scale data incorporation.

Related Experiment Videos

  • Providing network services (ftp, email, WWW) for data access and EBI's Sequence Retrieval System (SRS) for integrated database browsing.
  • Offering sequence similarity searching tools like BLAST, Fasta, and Blitz.

    • Main Results:

    • The EMBL database is continuously updated through international collaboration and diverse submission methods.
    • Free and open access to the latest sequence data is available via multiple network services.
    • Integrated database browsing and sequence similarity searching tools enhance data utility for researchers.

    Conclusions:

    • The EMBL Nucleotide Sequence Database is a vital, collaboratively maintained resource for the molecular biology community.
    • Its robust data submission, access, and analysis infrastructure supports global genomic research efforts.