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Related Experiment Videos

PseudoBase: structural information on RNA pseudoknots.

F H van Batenburg1, A P Gultyaev, C W Pleij

  • 1Group Theoretical Biology and Phylogenetics, Institute of Evolutionary and Ecological Sciences, Leiden University, Kaiserstraat 63, 2311GP Leiden, The Netherlands. batenburg@rulsfb.leidenuniv.nl

Nucleic Acids Research
|January 11, 2000
PubMed
Summary
This summary is machine-generated.

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PseudoBase is a comprehensive database for RNA pseudoknots, offering structural, functional, and sequence data. Recent updates include stem and loop size information, enhancing pseudoknot analysis.

Area of Science:

  • Bioinformatics
  • Structural Biology
  • Molecular Biology

Background:

  • RNA pseudoknots are crucial non-canonical secondary structures in RNA.
  • Understanding pseudoknot structure and function is vital for various biological processes.

Purpose of the Study:

  • To present PseudoBase, a curated database of RNA pseudoknots.
  • To provide comprehensive data including structural, functional, and sequence information.
  • To detail recent updates and enhancements to the database.

Main Methods:

  • Data compilation from various sources.
  • Database curation and organization.
  • Inclusion of structural parameters like stem and loop sizes.

Main Results:

Related Experiment Videos

  • PseudoBase stores thirteen key data items per pseudoknot.
  • The database includes sequence, stem positions, and reliability information.
  • New additions include stem and loop sizes, and sorted alternative entries.

Conclusions:

  • PseudoBase serves as a valuable resource for researchers studying RNA pseudoknots.
  • The database facilitates detailed analysis of pseudoknot structures and their properties.
  • Enhanced data on pseudoknot dimensions aids in comparative studies.