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A mild and selective cleavage of trityl ethers by CBr4-MeOH
1Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad, India. yadav@iict.ap.nic.in
Carbohydrate Research
|December 28, 2000
Abstract:
Trityl ethers are selectively deprotected to the corresponding alcohols in high yields by CBr4 in refluxing methanol under neutral reaction conditions. Other hydroxyl protecting groups like isopropylidene, allyl, benzyl, acetyl, benzoyl, methyl, tosyl, prenyl, propargyl, tert-butyldiphenylsilyl and p-methoxybenzyl ethers are unaffected.