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Updated: Jul 9, 2026

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Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
Published on: October 22, 2016
Electroencephalogram and repetitive transcranial magnetic stimulation
N N Boutros1, R M Berman, R Hoffman
1Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA. nash.boutros@yale.edu
Depression and Anxiety
|December 29, 2000
Summary
Continuous electroencephalogram (EEG) monitoring during repetitive transcranial magnetic stimulation (rTMS) is crucial for safety, especially when stimulation parameters exceed guidelines. This approach aids in understanding brain physiology and the effects of rTMS.
Area of Science:
- Neuroscience
- Clinical Neurophysiology
Background:
- Electroencephalogram (EEG) and evoked potentials (EPs) are used with repetitive transcranial magnetic stimulation (rTMS) for safety and to study magnetic stimulus effects.
- The combined use of EEG/EPs and rTMS is an underexplored area with potential for elucidating brain physiology.
Purpose of the Study:
- To report on the experience of continuous EEG sampling combined with rTMS in patients with psychiatric disorders.
- To support the use of continuous EEG monitoring as a safety measure in rTMS applications.
Main Methods:
- Continuous EEG monitoring was employed during rTMS sessions.
- The study included patients diagnosed with major depression, schizophrenia, and obsessive-compulsive disorder.
Main Results:
- Data gathered support the utility of continuous EEG monitoring during rTMS.
- Continuous EEG monitoring is particularly recommended when rTMS stimulation parameters fall outside established safety guidelines.
Conclusions:
- Combining EEG/EPs with rTMS holds potential for advancing our understanding of normal brain function.
- Continuous EEG monitoring is a valuable safety practice in rTMS, especially under non-standard stimulation parameters.

