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Clinical drug development--practical issues in clinical pharmacology studies
1Lilly-NUS Centre for Clinical Pharmacology Pte Ltd, Level 6 Clinical Research Centre (MD11), National University of Singapore, 10 Medical Drive, Singapore 117597.
Introduction:
Clinical pharmacology refers to the study of the safety, pharmacodynamic activity, mechanism of action, pharmacokinetics, metabolism and excretion of a drug in man.
Methods:
Selected review of topics that provide guidance on practical issues for researchers conducting non-therapeutic investigational research in humans.
Results:
Close attention to the issues highlighted is needed to ensure successful research in this area of drug development. Resources dedicated to the discipline can logically optimise efficiency and outcome.
Conclusions:
There is increasing opportunity for clinical pharmacological research, offering an interesting career option to young physicians.