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Updated: Aug 16, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Results of surgery for mitral insufficiency due to coronary artery disease
Insights
For patients with combined mitral and coronary artery disease, adding coronary artery revascularization to mitral valve surgery improves long-term survival and functional capacity, with similar short-term mortality rates.
Area of Science:
- Cardiovascular Surgery
- Cardiac Medicine
- Interventional Cardiology
Background:
- Combined mitral valve disease and coronary artery disease presents complex therapeutic challenges.
- Surgical decision-making requires careful consideration of risks and benefits for both conditions.
Purpose of the Study:
- To evaluate the impact of concurrent coronary artery revascularization on outcomes in patients undergoing mitral valve surgery.
- To compare short-term and long-term mortality and functional capacity between mitral valve surgery alone versus combined procedures.
Main Methods:
- Retrospective analysis of 26 patients with combined mitral and coronary artery disease.
- Patients were divided into two groups: mitral valve surgery only (Group 1) and mitral valve surgery with coronary artery revascularization (Group 2).
- Analysis included hospital mortality, late mortality, and functional capacity assessments.
Main Results:
- Hospital mortality was similar between the two groups, with higher rates for mitral valve replacement compared to repair.
- Patients with ejection fractions below 0.4 had a low survival rate (2/10) in Group 2.
- Late mortality was significantly higher in patients who did not receive revascularization, primarily due to myocardial infarction.
- Addition of revascularization improved functional capacity.
Conclusions:
- Coronary artery revascularization can be safely added to mitral valve surgery in selected patients, even with depressed ventricular function.
- Combined surgical approach improves long-term survival and functional outcomes compared to mitral valve surgery alone.
- Mitral valve repair may be associated with better short-term survival than replacement.
Abstract:
Twenty-six patients with combined mitral and coronary artery disease were divided into two groups: in group 1, only mitral valve surgery was performed, while in group 2, mitral valve surgery was performed along with coronary artery revascularization. Depressed ventricular function was not a contraindication to surgery; only 2 of 10 patients in group 2 with ejection fractions below 0.4 failed to survive operation. The hospital mortality was similar in both groups, and was higher for mitral valve replacement than mitral valve repair. Follow-up data revealed a higher incidence of late mortality in patients not undergoing revascularization, the main cause of death being myocardial infarction. The addition of revascularization also improved functional capacity.
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