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Mass screening for human papillomavirus type 16 infection in infertile couples
1Department of Obstetrics and Gynecology, Akita University School of Medicine, 1-1-1 Hondo, Akita City, 010-8543, Japan. tanaka-h@synap.ne.jp
Objective:
To investigate the prevalence of human papillomavirus (HPV) type 16 infection among in vitro fertilization (IVF) couples and to identify clinical conditions related to HPV infection.
Study Design:
The presence of HPV type 16 DNA in the uterine cervix of 192 women who underwent IVF and in 99 semen samples collected from their husbands were determined by the nested polymerase chain reaction method.
Results:
Ten women (5.5%) and 4 men (4.0%) were found to be HPV type 16 DNA positive. However, presence of the HPV type 16 DNA in the cervix or semen did not have any impact on IVF treatment variables, including presence of tubal factor, incidence of pregnancies and abortions, and semen quality. Only one of four women, whose partner's semen was HPV type 16 DNA positive, had a DNA positive cervix.
Conclusion:
These data provide useful information for counseling infertile couples with HPV type 16 infection.