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Rosette formation by clinical isolates of Plasmodium falciparum in serum-free medium

S J Rogerson1, P Katundu, M E Molyneux

  • 1Wellcome Trust Research Laboratories, Blantyre, Malawi. srogerson@malawi.net

Transactions of the Royal Society of Tropical Medicine and Hygiene
|December 29, 2000
PubMed
Abstract

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...