Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aspergillus flavus mitral valve endocarditis after lung abscess.

R G Demaria1, N Dürrleman, P Rispail

  • 1Thoracic and Cardiovascular Surgery Unit, Montpellier Teaching Hospital, France.

The Journal of Heart Valve Disease
|December 29, 2000
PubMed
Summary

This case report details a fatal Aspergillus flavus infection in an immunocompromised patient, highlighting the severe risks of fungal endocarditis and lung abscesses. Early surgical intervention is crucial for improving outcomes in such critical cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Persistent contamination of heater-cooler units for extracorporeal circulation cured by chlorhexidine-alcohol in water tanks.

The Journal of hospital infection·2018
Same author

Direct identification of molds by sequence analysis in fungal chronic rhinosinusitis.

Journal de mycologie medicale·2017
Same author

Clinical impact of NK-cell reconstitution after reduced intensity conditioned unrelated cord blood transplantation in patients with acute myeloid leukemia: analysis of a prospective phase II multicenter trial on behalf of the Société Française de Greffe de Moelle Osseuse et Thérapie Cellulaire and Eurocord.

Bone marrow transplantation·2017
Same author

[Biological diagnosis of onychomycoses. Direct examination after simplified technique of PAS staining].

Journal de mycologie medicale·2014
Same author

Assessment of caspofungin susceptibility of Candida glabrata by the Etest®, CLSI, and EUCAST methods, and detection of FKS1 and FKS2 mutations.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2014
Same author

Seven imported histoplasmosis cases due to Histoplasma capsulatum var. capsulatum: From few weeks to more than three decades asymptomatic period.

Journal de mycologie medicale·2014

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Cardiovascular Surgery

Background:

  • Bone marrow failure in a 16-year-old male secondary to chemotherapy for acute lymphoblastic leukemia.
  • Development of a left lung abscess with a bronchogastric fistula and mitral valve endocarditis.

Observation:

  • Microscopic examination revealed fungal hyphae in lung and heart specimens.
  • Fungal cultures identified Aspergillus flavus from both affected sites.
  • Surgical intervention included left lung lobectomy, fistula closure, and mechanical mitral valve replacement.

Findings:

  • Despite antifungal therapy and surgical management, the patient developed fatal systemic embolism.
  • Emboli contained Aspergillus flavus, consistent with the primary infection sites.

Related Experiment Videos

  • The case underscores the aggressive nature of Aspergillus flavus in immunocompromised hosts.

    • Implications:

    • Primary Aspergillus endocarditis in immunocompromised patients carries a grave prognosis.
    • Delayed surgical treatment and concurrent Aspergillus infections increase mortality risk.
    • This case emphasizes the need for prompt and aggressive management of invasive fungal infections in vulnerable populations.