Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experience with stentless aortic xenografts.

G B Luciani1, S Auriemma, G Casali

  • 1Division of Cardiac Surgery, University of Verona, Italy.

The Journal of Heart Valve Disease
|December 29, 2000
PubMed
Summary

Long-term results after aortic valve replacement (AVR) with freehand stentless xenografts show satisfactory survival and excellent freedom from structural valve deterioration. Functional improvement is expected even in elderly patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What can we learn from systematic segmental analysis of fetal heart by postmortem micro-CT: Is it time to change approach?

International journal of cardiology. Congenital heart disease·2024
Same author

Molecular effects of cardiac contractility modulation in patients with heart failure of ischemic aetiology uncovered by transcriptome analysis.

Frontiers in cardiovascular medicine·2024
Same author

Desmin mutations impact the autophagy flux in C2C12 cell in mutation-specific manner.

Cell and tissue research·2023
Same author

Mass-spring models for the simulation of mitral valve function: Looking for a trade-off between reliability and time-efficiency.

Medical engineering & physics·2017
Same author

Influence of the aortic valve leaflets on the fluid-dynamics in aorta in presence of a normally functioning bicuspid valve.

Biomechanics and modeling in mechanobiology·2015
Same author

Is TAVI superior to surgery in high-risk patients? Insight into the concept of individual risk assessment.

Minerva medica·2014

Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science
  • Clinical Outcomes Research

Background:

  • Aortic valve replacement (AVR) is a critical procedure for managing aortic valve disease.
  • Freehand stentless xenografts have been utilized in AVR, but their long-term performance requires definition.
  • Understanding outcomes is crucial for patient selection and prosthesis choice.

Purpose of the Study:

  • To evaluate the long-term clinical outcomes of patients undergoing aortic valve replacement using freehand stentless xenografts.
  • To assess survival rates, freedom from valve-related events, and structural valve deterioration.
  • To compare the performance of different xenograft models.

Main Methods:

  • Retrospective analysis of 376 consecutive patients undergoing stentless AVR between 1992 and 2000.

Related Experiment Videos

  • Inclusion of various xenograft types: Toronto SPV, Biocor PSB, and Cryolife-O'Brien.
  • Assessment of perioperative data, including associated procedures and operative times, with long-term follow-up.

    • Main Results:

    • In-hospital mortality was 2.7%; 33 late deaths occurred during follow-up (mean 40 months).
    • One, five, and seven-year survival rates were 96%, 83%, and 80%, respectively.
    • Freedom from structural valve deterioration was excellent (99% at 1 year, 92% at 7 years), with functional class improvement observed postoperatively.

    Conclusions:

    • Freehand stentless xenografts provide satisfactory long-term survival and freedom from adverse events in elderly patients undergoing AVR.
    • Excellent and comparable freedom from structural deterioration across xenograft models was noted.
    • Functional improvement can be anticipated post-AVR, even in an older patient cohort.