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Updated: Aug 11, 2026

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning
Published on: June 9, 2015
A new component in the a-wave of the human cone electroretinogram
1Department of Ophthalmology, Columbia University, New York City, NY 10032, USA. pg10@columbia.edu
Abstract:
The human cone electroretinogram (ERG) to a full field flash has been examined on a rod saturating background (17,000 photopic trolands). With strong stimuli, a negative wavelet appears in the falling phase of the a-wave. This response has a latency of 10-12 milliseconds, about 6-8 milliseconds after the start of the a-wave and just before the rising phase of the corneal positive b-wave begins. We suggest that it may represent a hyperpolarizing response of second order retinal neurons.
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