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Homozygous factor V Leiden mutation in a woman with multiple adverse pregnancy outcomes
H U Pauer1, J Neesen, M Schloesser
1Department of Gynecology and Obstetrics, University of Goettingen, Germany.
Archives of Gynecology and Obstetrics
|December 29, 2000
Abstract:
We report a case with one intrauterine fetal death (IUFD) at 32 weeks of gestation, one premature delivery at the same week, and one abortion of unknown etiology at 12 weeks of gestation. We discuss that the presence of homozygosity for Factor V Leiden may be associated with placental insufficiency in this woman. Application of anticoagulant therapy may have been beneficial in her current pregnancy.