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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Related Experiment Video

Updated: Jul 12, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

The Geriatric Pain Measure: validity, reliability and factor analysis.

B A Ferrell1, W M Stein, J C Beck

  • 1UCLA School of Medicine, Los Angeles, California, USA.

Journal of the American Geriatrics Society
|December 29, 2000
PubMed
Summary
This summary is machine-generated.

A new Geriatric Pain Measure (GPM) effectively assesses multidimensional pain in older adults. This valid and reliable tool aids comprehensive geriatric assessments for better pain management.

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Last Updated: Jul 12, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Area of Science:

  • Gerontology
  • Pain Management
  • Geriatric Assessment

Background:

  • Pain is a complex experience requiring more than intensity evaluation.
  • No multidimensional pain measure exists for older adults in geriatric assessments.

Purpose of the Study:

  • To develop and validate a multidimensional pain assessment instrument for older adults.
  • Evaluate the reliability and validity of the Geriatric Pain Measure (GPM).

Main Methods:

  • Instrument development and evaluation using a series of steps.
  • 176 geriatric clinic outpatients (mean age 84) participated.
  • Included GPM, McGill Pain Questionnaire, geriatric scales, and clinical data.

Main Results:

  • GPM showed high reliability (alpha=0.9445) and internal consistency.
  • Concurrent validity (r=0.6269) and test-retest reliability (r=0.9018) were confirmed.
  • Factor analysis identified five pain components: Intensity, Disengagement, Ambulation, Strenuous Activities, and Other Activities.

Conclusions:

  • The 24-item GPM is easy to administer and shows strong validity and reliability.
  • The GPM is a valuable tool for multidimensional geriatric pain assessment.