Related Experiment Videos
Diterpene from Baccharis trimera with a relaxant effect on rat vascular smooth muscle
L M Torres1, M T Gamberini, N F Roque
1Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, SP, Brazil. luce.farm@infar.epm.br
Phytochemistry
|December 29, 2000
Abstract:
A bioassay monitored fractionation of a chloroform extract from the aerial parts of Baccharis trimera yielded a mixture that blocked the Ca2+-induced contractions of KCl- depolarized rat portal vein preparations. Pharmacological tests of two pure compounds isolated from the mixture revealed the dilactonic clerodane diterpene as the active compound.