Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immune function.

T A Fleisher1, J J Bleesing

  • 1Department of Laboratory Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

Pediatric Clinics of North America
|December 29, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A 20 Year Clinical and Laboratory Study of Familial B-Chronic Lymphocytic Leukemia in a Single Kindred.

Leukemia & lymphoma·2016
Same author

Loss of B Cells in Patients with Heterozygous Mutations in IKAROS.

The New England journal of medicine·2016
Same author

Activated STING in a vascular and pulmonary syndrome.

The New England journal of medicine·2014
Same author

Alternative donor SCT for the treatment of MHC class II deficiency.

Bone marrow transplantation·2012
Same author

Outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome.

Bone marrow transplantation·2012
Same author

The relationship between alloimmunization and posttransfusion granulocyte survival: experience in a chronic granulomatous disease cohort.

Transfusion·2010

The innate and adaptive immune systems protect the body from microbes. Understanding these systems and their mediators is key to developing new therapies for immune deficiencies and inflammatory diseases.

Area of Science:

  • Immunology
  • Microbiology

Background:

  • The innate and adaptive immune systems are crucial for host defense against microbial pathogens.
  • These systems have evolved to provide rapid and specific protection throughout a host's lifetime.

Purpose of the Study:

  • To highlight the cooperative interaction between innate and adaptive immunity.
  • To discuss the role of immune system defects in primary immune deficiencies.
  • To explore the immune system's involvement in inflammatory disorders like allergies and autoimmune diseases.

Main Methods:

  • Review of current literature on innate and adaptive immunity.
  • Discussion of primary immune deficiencies.
  • Exploration of the immune system's role in pathogenesis of inflammatory conditions.

Related Experiment Videos

Main Results:

  • Defects in immune pathways lead to severe consequences, exemplified by primary immune deficiencies.
  • The immune system is central to the pathogenesis of allergic and autoimmune diseases.

Conclusions:

  • Increased understanding of the immune system and its mediators will drive the development of novel therapies.
  • Cooperative interactions between innate and adaptive immunity are essential for effective host defense.