Related Experiment Video

Updated: Oct 10, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension
05:57

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Published on: May 17, 2024

Blood pressure control in Japanese hypertensives with or without type 2 diabetes mellitus

S Katayama1, M Inaba, T Morita

  • 1Fourth Department of Medicine, Saitama Medical School, Iruma-gun, Japan.

Hypertension Research : Official Journal of the Japanese Society of Hypertension
|December 29, 2000
PubMed

Insights

Blood pressure control is insufficient in Japanese patients with hypertension, including those with type 2 diabetes. Less than 130/85 mmHg was achieved in only 10% of patients, highlighting a need for improved hypertension management in high-risk groups.

Area of Science:

  • Cardiology
  • Endocrinology
  • Hypertension Research

Background:

  • Type 2 diabetes mellitus and hypertension significantly increase cardiovascular disease risk.
  • Current hypertension guidelines recommend target blood pressure below 130/85 mmHg.

Purpose of the Study:

  • To assess blood pressure control in Japanese hypertensive patients with and without type 2 diabetes mellitus.
  • To understand antihypertensive medication prescribing patterns in these patient groups.

Main Methods:

  • Survey of 200 physicians from the Japanese Society of Hypertension and Japanese Diabetes Society.
  • Data collected on 954 hypertensive patients with type 2 diabetes and 371 without.
  • Analysis of achieved blood pressure and number/type of antihypertensive agents used.

Main Results:

  • Achieved blood pressure below 140/90 mmHg was 40.5% in non-diabetics and 38.3% in diabetics.
  • Only 10.8% of non-diabetics and 11.4% of diabetics reached blood pressure below 130/85 mmHg.
  • Physicians used more ACE inhibitors and alpha-blockers in diabetics, while Ca-antagonists were common in both groups.

Conclusions:

  • Despite considering metabolic effects, blood pressure control remains inadequate in Japanese hypertensive patients, including those with diabetes.
  • A significant gap exists in achieving target blood pressure levels, necessitating improved hypertension management strategies.
  • Enhanced blood pressure control is crucial for high-risk populations like diabetic hypertensive patients to reduce cardiovascular events.

More Related Videos

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.