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Chemotherapy with gemcitabine in patients with advanced gallbladder carcinoma
A Teufel1, T Lehnert, W Stremmel
1Medizinische Klinik und Poliklinik der Universität, Heidelberg.
Abstract
Background:
Advanced or metastatic gallbladder carcinoma is regarded not much sensitive to chemotherapy. Standard chemotherapy regimens have not been established up to now.
Patients:
We report on 5 patients with advanced gallbladder carcinoma who received chemotherapy with gemcitabine.
Results:
Of these 5 patients, 3 demonstrated a partial remission and stable disease was achieved in another patient. Only one patient had no benefit from treatment with gemcitabine.
Conclusion:
We conclude that gemcitabine may be an effective drug in the palliative treatment of gallbladder cancer, and thus its efficiency warrants evaluation in further studies.