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Ross syndrome plus: beyond horner, Holmes-Adie, and harlequin
R K Shin1, S L Galetta, T Y Ting
1Departments of Neurology, Hospital of the University of Pennsylvania, Philadelphia 19104-4283, USA. shirobk@mail.med.upenn.edu
Background:
Ross syndrome is an uncommon disorder characterized by the triad of segmental anhidrosis, hyporeflexia, and tonic pupils.
Methods:
The authors describe the clinical findings of five patients with Ross syndrome and detail the results of their pharmacologic and autonomic testing.
Results:
In four patients, the classic findings of Ross syndrome were accompanied by Horner's syndrome. Other symptoms of dysautonomia were also common.
Conclusions:
These findings suggest that Ross syndrome is a dysautonomic condition of varying expression resulting from a generalized injury to ganglion cells or their projections.
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