Related Experiment Video
Updated: Oct 10, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
HLA class II genotypes in Mexican Mestizos with familial and nonfamilial multiple sclerosis
C Alvarado-de la Barrera1, J Zúñiga-Ramos, J A Ruíz-Morales
1Departments of Immunology and Rheumatology, Instituto Nacional de la Nutrición Salvador Zubirán, Tlalpan, México.
Abstract:
Predisposition to MS is associated with the HLA-DR2 antigen in white patients. The authors investigated the genetic factors behind the increasing frequency of MS in the Mexican population. HLA-DR and DQ were analyzed in 17 patients with MS, 15 of their first-degree relatives, and 99 healthy ethnically matched controls. DR2 or DR3 was found in 15 of 17 patients. In controls, both alleles had frequencies less than 0.05. MS in Mexican patients was associated with HLA-DR2 and DR3.
Related Concept Videos
Multiple Sclerosis l: Introduction
Genetic Lingo
Multiple Allele Traits
