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Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson's disease
V Fraix1, P Pollak, N Van Blercom
1Department of Clinical and Biological Neurosciences, University Hospital of Grenoble, and INSERM U318, Joseph Fourier University, France.
Neurology
|January 3, 2001
Abstract:
Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.