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Updated: Aug 11, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Rupture of the posterior wall of the left ventricle after mitral valve replacement
Abstract:
Rupture of the posterior wall of the left ventricle is an unusual but often lethal complication following mitral valve replacement (MVR). We have encountered it six times with a 100 per cent mortality rate in a series of 1,154 operations for MVR. Sites of rupture were located at the base of the resected papilary muscle or close to the artioventricular groove in the area adjacent to the resected posterior mitral leaflet. T stongly indicates the overzealous resection of the mitral leaflets and papillary muscle as an important eitiologic factor. Other possible etiologic factors are discussed and important pitfalls to be avoided during MVR are stressed.
Insights
Posterior left ventricular wall rupture is a rare but fatal complication after mitral valve replacement (MVR). This study found a 100% mortality rate in six cases, highlighting surgical technique as a key factor.
Area of Science:
- Cardiovascular Surgery
- Cardiac Pathology
Background:
- Posterior left ventricular (LV) wall rupture is a rare but devastating complication post-mitral valve replacement (MVR).
- This complication carries a high mortality rate, necessitating a thorough understanding of its etiology and prevention.
Purpose of the Study:
- To investigate the incidence, characteristics, and potential causes of posterior LV wall rupture following MVR.
- To identify critical surgical pitfalls to avoid during MVR procedures to prevent this complication.
Main Methods:
- Retrospective analysis of patients who underwent MVR.
- Detailed review of surgical records and autopsy findings for cases of posterior LV wall rupture.
Main Results:
- Six cases of posterior LV wall rupture were identified in 1,154 MVR operations, resulting in a 100% mortality rate.
- Rupture sites were consistently located at the base of resected papillary muscles or near the atrioventricular groove.
- Overzealous resection of mitral leaflets and papillary muscles was identified as a significant etiologic factor.
Conclusions:
- Posterior LV wall rupture is a critical complication of MVR with a uniformly fatal outcome.
- Surgical technique, particularly the extent of mitral leaflet and papillary muscle resection, is crucial in preventing this complication.
- Adherence to meticulous surgical techniques and avoidance of specific pitfalls are essential for patient safety during MVR.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation I: Introduction
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Stenosis I: Introduction
Mitral Stenosis III: Medical Management

