Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ictal generalized rhythmic alpha activity during non-convulsive status epilepticus.

J Bauer1, M Neumann, H W Kölmel

  • 1Department of Epileptology, University of Bonn, Germany. Juergen.Bauer@meb.uni-bonn.de

European Journal of Neurology
|January 3, 2001
PubMed
Summary

This study details a rare form of non-convulsive status epilepticus with a unique EEG pattern in two epilepsy patients. Treatment with lamotrigine and valproate significantly reduced seizure frequency.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rasmussen encephalitis with ipsilateral brain stem involvement in an adult patient.

BMJ case reports·2025
Same author

Volumetry of Mesiotemporal Structures Reflects Serostatus in Patients with Limbic Encephalitis.

AJNR. American journal of neuroradiology·2019
Same author

Cognitive outcome of pediatric epilepsy surgery across ages and different types of surgeries: A monocentric 1-year follow-up study in 306 patients of school age.

Seizure·2019
Same author

Cognitive outcomes more than 5 years after temporal lobe epilepsy surgery: Remarkable functional recovery when seizures are controlled.

Seizure·2018
Same author

An online adaptive screening procedure for selective neuronal responses.

Journal of neuroscience methods·2017
Same author

Gait instability in valproate-treated patients: Call to measure ammonia levels.

Acta neurologica Scandinavica·2017

Area of Science:

  • Neurology
  • Epileptology
  • Clinical Neurophysiology

Background:

  • Epilepsy is a chronic neurological disorder characterized by recurrent seizures.
  • Non-convulsive status epilepticus (NCSE) is a prolonged seizure state without convulsions, posing diagnostic challenges.
  • Understanding diverse NCSE presentations is crucial for effective management.

Observation:

  • Two patients with epilepsy presented with recurrent NCSE exhibiting an uncommon ictal electroencephalographic (EEG) pattern.
  • The EEG pattern was characterized by monomorphic alpha activity, generalized and bilateral.
  • Clinical manifestations included altered responsiveness, amnesia, and eyelid myoclonia in one patient.

Findings:

  • The NCSE episodes began and concluded abruptly, both clinically and electroencephalographically.

Related Experiment Videos

  • One patient with early-onset epilepsy showed delayed intellectual development, while the other developed memory impairment.
  • Combination therapy with lamotrigine and valproate markedly decreased the frequency of NCSE in both individuals.

    • Implications:

    • This case series highlights a distinct subtype of generalized NCSE with an unusual EEG signature.
    • The findings underscore the importance of comprehensive neurophysiological and neuropsychological assessments in diagnosing and managing complex epilepsy cases.
    • Effective treatment strategies, including the combination of lamotrigine and valproate, can significantly improve outcomes for patients with this specific NCSE presentation.