Related Experiment Videos
X inactivation: Tsix and Xist as yin and yang
1University of California San Francisco, Department of Biochemistry and Biophysics, 513 Parnassus Avenue, Box 0448, San Francisco, California 94143, USA.
Current Biology : CB
|January 4, 2001
Abstract:
A new study shows that expression of Tsix, an antisense Xist gene, can be controlled by imprinting, and that high Tsix activity during X inactivation can protect the future active X chromosome from silencing by Xist. Tsix and Xist seem to have a yin and yang relationship, with opposite effects on X inactivation.