Proton MR spectroscopy of the brain
S R Maheshwari1, G M Fatterpekar, M Castillo
1Department of Radiology, University of North Carolina Schools of Medicine and Dentistry, Chapel Hill 27599-7510, USA.
Seminars in Ultrasound, CT, and MR
|January 4, 2001
Summary
Magnetic resonance spectroscopy (MRS) is a noninvasive tool for monitoring brain biochemical changes. This reimbursable clinical technique is valuable for diagnosing and tracking neurological diseases.
Area of Science:
- Neuroimaging
- Biomedical Engineering
- Clinical Diagnostics
Background:
- Magnetic resonance spectroscopy (MRS) offers noninvasive monitoring of brain biochemistry.
- It enables serial assessment of metabolic changes in neurological diseases.
- MRS has achieved clinical acceptance and is a reimbursable procedure.
Purpose of the Study:
- To review the fundamental physics and techniques of MRS.
- To discuss various MRS pulse sequences.
- To highlight the clinical applications of MRS in neurology.
Main Methods:
- Review of MRS physics principles.
- Description of common MRS pulse sequences.
- Compilation of clinical use cases for MRS.
Main Results:
- MRS is an established, noninvasive method for brain metabolic analysis.
- The technique is applicable to serial monitoring of disease progression.
- Clinical reimbursement validates its utility.
Conclusions:
- MRS is a versatile and valuable tool in clinical neurology.
- Understanding MRS physics and techniques is crucial for its application.
- Further integration of MRS into clinical practice is expected.
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