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trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease
A S Buchovsky1, O Campetella, G Russomando
1Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Clinical and Diagnostic Laboratory Immunology
|January 4, 2001
Abstract:
For the diagnosis of Chagas' disease, the trans-sialidase inhibition assay was able to resolve the results for samples with borderline results, to detect as positive 60% of samples that were negative by conventional serology, and to discriminate idiopathic from chagasic megaviscera or cardiopathy. No cross-reaction with sera from patients with other diseases was observed.

