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[Nutrition and chronic respiratory failure].
1Service de Pneumologie et Réanimation, Hôtel-Dieu, 1, place du Parvis-Notre-Dame, 75181 Paris Cedex 04.
Annales De Medecine Interne
|January 5, 2001
Summary
Protein calorie malnutrition is common in chronic obstructive pulmonary disease (COPD) patients, leading to poor prognosis. Oral supplementation may improve nutritional status and exercise tolerance in ambulatory COPD patients.
Area of Science:
- Pulmonology
- Nutritional Science
- Metabolism
Context:
- Protein calorie malnutrition is prevalent in patients diagnosed with chronic obstructive pulmonary disease (COPD).
- Hypermetabolism, driven by increased respiratory muscle oxygen consumption, is a primary mechanism.
- Malnutrition negatively impacts prognosis regardless of patient age or respiratory function.
Purpose:
- To investigate the consequences of malnutrition in COPD patients.
- To evaluate the efficacy of oral supplementation and anabolic drugs in malnourished COPD patients.
Summary:
- Malnutrition in COPD patients results in respiratory muscle atrophy, reduced strength, decreased exercise performance, and diminished quality of life.
- It may also increase the risk of community-acquired and nosocomial pneumonia.
- Long-term oral nutritional supplementation shows potential for improving nutritional status and exercise tolerance in ambulatory COPD patients.
- Anabolic drugs, including recombinant growth hormone, have not demonstrated significant benefits in this patient group.
Impact:
- Highlights the detrimental effects of malnutrition on COPD patients.
- Suggests oral supplementation as a viable strategy for nutritional support and functional improvement.
- Indicates a lack of evidence for anabolic drugs in treating malnutrition in COPD.