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[Reactive hemaphagocytic syndrome in a patient with midline NK-cell lymphoma]
S Seiberras1, G Hilbert, D Gruson
1Service de Médecine Interne, CHU Pellegrin, Bordeaux.
Annales De Medecine Interne
|January 5, 2001
Abstract:
Different etiologies have been shown to underly lethal midline granuloma. Evidence of natural killer cell lymphoma is obtained by immunolabeling and molecular biology studies. The tumor has a characteristic immunophenotype and genotype. This clinicopathological entity is highly associated with Epstein-Barr virus (EBV). We present the case of a patient with EBV associated with nasal-type natural-killer cell lymphoma and a coexisting hemophagocytic syndrome.