Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Imaging residue transfer into egg yolks.

D J Donoghue1, K Myers

  • 1Division of Animal Research, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, Maryland 20708, USA. ddonoghue@comp.uark.edu

Journal of Agricultural and Food Chemistry
|January 16, 2001
PubMed
Summary

Drug residues are incorporated and stored in ring structures within developing egg yolks. This sequestration poses food safety risks, as residues can contaminate eggs for weeks after a single dose.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Cost of Homecare Personal Support Worker Turnover.

Healthcare management forum·2026
Same author

The Cost of Turnover in Home Healthcare: A Conceptual Model.

Healthcare management forum·2026
Same author

Changing lives, dynamic plans: Prospective assessment of 12-month changes in pregnancy timing intentions and personal circumstances using data from HER Salt Lake.

PloS one·2021
Same author

The swelling behavior of the mouse cervix: Changing kinetics with osmolarity and the role of hyaluronan in pregnancy.

Acta biomaterialia·2021
Same author

Carvacrol attenuates Campylobacter jejuni colonization factors and proteome critical for persistence in the chicken gut.

Poultry science·2020
Same author

Genome-Wide Association Study Identifies Single Nucleotide Polymorphism Markers Associated with Mycelial Growth (at 15, 20, and 25°C), Mefenoxam Resistance, and Mating Type in <i>Phytophthora infestans</i>.

Phytopathology·2019

Area of Science:

  • Veterinary Pharmacology
  • Food Safety Science
  • Biomedical Imaging

Background:

  • Developing egg yolks are recognized as significant storage sites for chemical residues.
  • Understanding residue incorporation into eggs is crucial for food safety assessments.

Purpose of the Study:

  • To visualize the incorporation and compartmentalization of drug residues within developing egg yolks.
  • To assess the potential for drug sequestration and subsequent release into eggs.

Main Methods:

  • Administered the drug magnevist to hens to track residue transfer into developing egg yolks.
  • Utilized high-resolution magnetic resonance imaging (MRI) on a 1.5 T clinical scanner to visualize drug residues.
  • Employed a magnetization-prepared, rapid acquisition, gradient-recalled-echo (MPRAGE) pulse sequence for image acquisition.

Main Results:

  • Visual evidence confirmed the incorporation and compartmentalization of drug residues into distinct ring structures within developing egg yolks.
  • Drug residues were observed within individual yolk structures, indicating sequestration.

Conclusions:

  • Drug residues can be sequestered into specific structures within developing egg yolks.
  • This sequestration has significant food safety implications, with potential for prolonged contamination of eggs.

Related Experiment Videos