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Alternaria-associated asthma.

F Fung1, D Tappen, G Wood

  • 1Sharp Rees-Stealy Medical Group and University of California, San Diego, San Diego, California, USA.

Applied Occupational and Environmental Hygiene
|January 6, 2001
PubMed
Summary
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Mold allergens like Alternaria can trigger asthma and allergic reactions in offices. Prompt identification and removal of mold, such as Alternaria in an air conditioner unit, resolved an employee's respiratory issues.

Area of Science:

  • Occupational Health
  • Environmental Science
  • Allergology

Background:

  • Mold allergens, particularly Alternaria, are increasingly recognized as contributors to indoor allergic reactions, rhinitis, and asthma.
  • Asthma exacerbation in an employee prompted an investigation into potential environmental triggers in the workplace.

Observation:

  • An industrial hygiene study and bioaerosol testing identified several mold allergens.
  • Medical evaluations, including skin prick tests and radioallergosorbent tests (RAST), indicated Alternaria as the causative agent for the employee's respiratory reaction.
  • Alternaria was found in the air conditioner unit's drip pan.

Findings:

  • Remedial actions successfully removed Alternaria from the air conditioner unit.
  • Post-remediation bioaerosol sampling confirmed the absence of Alternaria.

Related Experiment Videos

  • The employee experienced symptom resolution and returned to work without recurrence of asthma exacerbation.

    • Implications:

    • This case highlights the importance of a multi-faceted approach, including medical diagnosis, exposure evidence, environmental assessment, and remediation, for managing occupational and environmental diseases.
    • Effective collaboration between industrial hygienists and occupational health physicians is crucial for preventing and treating such conditions.
    • Environmental mold contamination, even in seemingly minor locations like AC drip pans, can significantly impact employee health and necessitate targeted remediation efforts.