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Computed tomographic angiography and computed tomographic perfusion imaging of hyperacute stroke
1Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.
Topics in Magnetic Resonance Imaging : TMRI
|January 6, 2001
Summary
Noncontrast CT (NCCT) and CT angiography/perfusion (CTA/CTP) rapidly triage acute stroke patients. These imaging techniques improve early stroke detection and guide reperfusion therapy decisions, enhancing patient outcomes.
Area of Science:
- Neuroradiology
- Emergency Medicine
- Stroke Imaging
Background:
- Hyperacute stroke requires rapid diagnosis and treatment.
- Timely triage is crucial for effective reperfusion therapies.
Purpose of the Study:
- To review the roles of noncontrast computed tomography (NCCT) and CT angiographic/CT perfusion (CTA/CTP) in hyperacute stroke patient triage.
- To evaluate the effectiveness of these imaging modalities in guiding therapeutic decisions.
Main Methods:
- Review of current literature on NCCT and CTA/CTP in acute stroke.
- Analysis of imaging findings and their correlation with treatment and outcomes.
Main Results:
- NCCT detects early stroke, with sensitivity enhanced by specific window settings.
- CTA/CTP accurately diagnoses ischemia and localizes thrombus, surpassing clinical assessment.
- CT perfusion hypodensity volume predicts infarct size and clinical outcome.
Conclusions:
- NCCT and CTA/CTP are vital for rapid stroke triage and treatment selection.
- Imaging findings guide decisions for intravenous thrombolysis, intra-arterial thrombolysis, and other interventions.