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Carcinoma in situ in the testis
M Rørth1, E Rajpert-De Meyts, L Andersson
1Department of Oncology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark. mroerth@rh.dk
Scandinavian Journal of Urology and Nephrology. Supplementum
|January 6, 2001
Abstract:
Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.