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The molecular biology of CD1
1Institute of Child Health, 30 Guilford St, WC1N 1EH London, UK and MRC Laboratory of Molecular Biology, Hills Rd, Cambridge, CB2 2QH, UK. fcalabi@ich.ucl.ac.uk
Seminars in Immunology
|January 9, 2001
Abstract:
CD1 were the first human differentiation antigens to be identified by monoclonal antibodies. In this review, we summarize some key results from the molecular study of CD1, with particular reference to their relationship to MHC antigens, and to the existence of two distinct groups of CD1 molecules.