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Updated: Aug 15, 2026

A Method For Production of Recombinant mCD1d Protein in Insect Cells.
Published on: December 11, 2007
CD1 molecules and CD1-dependent T cells in bacterial infections: a link from innate to acquired immunity?
1Max-Planck-Institute for Infection Biology, Berlin, Germany. schaible@mpiib-berlin.mpg.de
Abstract:
The MHC class I-like, non-polymorphic CD1 molecules represent a novel system for the presentation of glycolipid antigens to T lymphocytes. CD1-mediated T cell responses appear to play distinct roles during bacterial infections such as in tuberculosis. This review deals with two aspects of CD1-mediated immune reactions. First we discuss the role of group II CD1-dependent NK T cells in bacterial infection. Second, we provide an insight into differential intracellular meeting points for antigen processing between group I CD1 molecules, mycobacteria and mycobacterial glycolipid antigens.
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