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Parental pediatric corticosteroid preferences.
J M Isa1, G K Wong, S S Teraoka
1Department of Pediatrics, University of Hawaii John A. Burns School of Medicine, Kapiolani Medical Center for Women and Children, Honolulu, HI 96826, USA.
The American Journal of Emergency Medicine
|January 9, 2001
Summary
Parental preference for pediatric asthma medication revealed taste is crucial. The less concentrated, better-tasting oral prednisolone syrup was preferred over intramuscular or more concentrated options.
Area of Science:
- Pediatric pharmacology
- Asthma management
- Clinical trial design
Background:
- Corticosteroids are essential in acute asthma care.
- Prednisolone offers intramuscular (IM) and oral administration routes.
- Oral prednisolone is available in varying concentrations.
Purpose of the Study:
- To assess parental preference for prednisolone preparations.
- To evaluate the impact of administration route, taste, and volume on preference.
- To inform optimal corticosteroid treatment plans for pediatric asthma.
Main Methods:
- Survey and taste-testing of accompanying adults (AAs) of pediatric patients.
- Evaluation of preferences based on route (IM vs. oral), taste, and volume.
- Comparison of concentrated vs. less concentrated oral prednisolone formulations.
Main Results:
- 43% of AAs preferred IM corticosteroids, 40% preferred oral.
- Initially, 94% preferred the more concentrated oral syrup.
- After tasting, 96% preferred the less concentrated, better-tasting syrup, indicating taste is a key factor.
Conclusions:
- Taste significantly influences parental preference for oral prednisolone formulations.
- The less concentrated, better-tasting syrup is highly preferred over concentrated or IM options.
- Incorporating taste and route preferences can optimize pediatric asthma treatment plans.
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