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Related Experiment Videos

Parental pediatric corticosteroid preferences.

J M Isa1, G K Wong, S S Teraoka

  • 1Department of Pediatrics, University of Hawaii John A. Burns School of Medicine, Kapiolani Medical Center for Women and Children, Honolulu, HI 96826, USA.

The American Journal of Emergency Medicine
|January 9, 2001
PubMed
Summary

Parental preference for pediatric asthma medication revealed taste is crucial. The less concentrated, better-tasting oral prednisolone syrup was preferred over intramuscular or more concentrated options.

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Area of Science:

  • Pediatric pharmacology
  • Asthma management
  • Clinical trial design

Background:

  • Corticosteroids are essential in acute asthma care.
  • Prednisolone offers intramuscular (IM) and oral administration routes.
  • Oral prednisolone is available in varying concentrations.

Purpose of the Study:

  • To assess parental preference for prednisolone preparations.
  • To evaluate the impact of administration route, taste, and volume on preference.
  • To inform optimal corticosteroid treatment plans for pediatric asthma.

Main Methods:

  • Survey and taste-testing of accompanying adults (AAs) of pediatric patients.
  • Evaluation of preferences based on route (IM vs. oral), taste, and volume.
  • Comparison of concentrated vs. less concentrated oral prednisolone formulations.

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Main Results:

  • 43% of AAs preferred IM corticosteroids, 40% preferred oral.
  • Initially, 94% preferred the more concentrated oral syrup.
  • After tasting, 96% preferred the less concentrated, better-tasting syrup, indicating taste is a key factor.

Conclusions:

  • Taste significantly influences parental preference for oral prednisolone formulations.
  • The less concentrated, better-tasting syrup is highly preferred over concentrated or IM options.
  • Incorporating taste and route preferences can optimize pediatric asthma treatment plans.