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Dynamics of peroxisome assembly and function

V I Titorenko1, R A Rachubinski

  • 1Dept of Cell Biology, University of Alberta, Edmonton, T6G 2H7, Alberta, Canada

Trends in Cell Biology
|January 9, 2001
PubMed

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Mitochondria, chloroplasts, and gram-negative bacteria have transmembrane, beta-barrel proteins called porins to mediate the free diffusion of ions and metabolites across the membrane. Mitochondrial porin precursors contain conserved amino acid sequences called beta signals at their C-terminal. Beta signals have a  motif of PoXGXXHyXHy (Po-Polar, X-Any amino acid, G-Glycine, Hy-LargeHydrophobic), which are crucial for precursor recognition to initiate precursor assembly. Beta-barrel precursors...
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