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Bacillary angiomatosis in HIV-infected patients--an epidemiological and clinical study
A Plettenberg1, T Lorenzen, B T Burtsche
1Allgemeines Krankenhaus St. Georg, Hamburg, Deutschland. Plettenberg@compuserve.com
Background:
No data were available on the epidemiological and clinical characteristics of bacillary angiomatosis (BA) in Germany.
Objective:
To determine epidemiological and clinical data on HIV-associated BA.
Methods:
A chart review of all BA cases between 1990 and 1998 was performed in 23 German AIDS treatment units.
Results:
A total of 21 cases of BA was diagnosed. During this period, the participating HIV centers treated about 17,000 HIV-infected patients. As a result, a BA prevalence of 1.2 cases/1,000 patients can be assumed. 19 BA were localized in the skin; in 5 cases bones and in 4 cases the liver were involved. Out of 20 patients who received antibiotic therapy, 13 had complete remission. The median time of duration up to complete remission was 32 days (9-82). During the follow-up of the 20 patients, 7 relapses were observed.
Conclusion:
BA is a rare HIV-associated disease with a prevalence of 1,2 cases/1,000 patients in the presented study.